Common and rare variants in multifactorial susceptibility to common diseases
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چکیده
منابع مشابه
Common and rare variants in alcohol dependence.
c h a b c M any lines of evidence converge to show that genetics makes a substantial contribution to the risk for alcohol dependence, explaining about 60% of the variance. However, alcohol dependence is not a Mendelian trait with a simple pattern of inheritance, nor is it deterministic. It is a complex trait like most psychiatric diseases and other common diseases, with both genetic and environ...
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ژورنال
عنوان ژورنال: Nature Genetics
سال: 2008
ISSN: 1061-4036,1546-1718
DOI: 10.1038/ng.f.136